Dr. Julian Parkhill, Sanger Institute
Signatures of emergence and transmission in bacterial pathogens
Dr. Parkhill has been involved on analysis of transmission and emergence of pathogens for almost 2 decades now. A glance through his publication record shows involvement in epidemic analysis and antimicrobial resistance in Burkholderia, Campylobacter, Neisseria, Legionella, Cholera, Mycobacteria and has assisted in the development of tools and analysis for better visualization and annotation of sequence data, faster phylogenetic analysis, whole genome sequencing, SNPs and AMR, population structure and much more.
Today we looked at Extraintestinal Pathogenic E. coli (ExPEC) and Uropathogenic E. coli (UPEC), and once again we are looking at ST131 in particular as we did in the AMR Highlights blog.
Signatures of emergence and transmission in bacterial pathogensDr. Parkhill has been involved on analysis of transmission and emergence of pathogens for almost 2 decades now. A glance through his publication record shows involvement in epidemic analysis and antimicrobial resistance in Burkholderia, Campylobacter, Neisseria, Legionella, Cholera, Mycobacteria and has assisted in the development of tools and analysis for better visualization and annotation of sequence data, faster phylogenetic analysis, whole genome sequencing, SNPs and AMR, population structure and much more.
Today we looked at Extraintestinal Pathogenic E. coli (ExPEC) and Uropathogenic E. coli (UPEC), and once again we are looking at ST131 in particular as we did in the AMR Highlights blog.
- ST131 clones are said to have emerged in 2000, sequentially acquiring fluoroquinolone resistance followed by beta-lactam resistance (blaCTXM15), rapidly expanded and have remained stable ever since in terms of population size.
But is this really 'emergence'?
